By: 
Karin Schumacher, COS, Heidelberg University, Germany
Host: 
Eva Sundberg
Location: 
Lecture hall A281, Uppsala BioCentre, Ultuna
Date: 
2015-12-10
Time: 
14:00 - 15:00
SEMINAR CANCELLED DUE TO ILLNESS

Live and in colour: Improved tools for multi-parameter imaging

The concentration of two ions, Ca2+ and H+, affects almost all biological processes and dynamic changes in [Ca2+] and pH are integral components of many signalling pathways. My lab studies the transport machinery that controls cellular pH and Ca2+ -homeostasis and we use genetically-encoded sensors to visualize their spatio-temporal dynamics. In my presentation, I will cover our recent work on pH-regulation in the endomembrane system as well as our attempts to establish transgenic lines that allow monitoring of multiple parameters including pH, Ca2+, ROS and ATP.